Fitting and comparison of calcium-calmodulin kinetic schemes to a common data set using non-linear mixed effects modelling.

Calmodulin is a calcium binding protein that is essential in calcium signalling in the brain. There are many computational models of calcium-calmodulin binding that capture various calmodulin features. However, existing models have generally been fit to different data sets, with some publications no...

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Bibliographic Details
Main Authors: Domas Linkevicius, Angus Chadwick, Guido C Faas, Melanie I Stefan, David C Sterratt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0318646
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