CENP-A/CENP-B uncoupling in the evolutionary reshuffling of centromeres in equids
Abstract Background While CENP-A is the epigenetic determinant of the centromeric function, the role of CENP-B, a centromeric protein binding a specific DNA sequence, the CENP-B-box, remains elusive. In the few mammalian species analyzed so far, the CENP-B box is contained in the major satellite rep...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-02-01
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Series: | Genome Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13059-025-03490-0 |
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