High-dose thiamine supplementation ameliorates obesity induced by a high-fat and high-fructose diet in mice by reshaping gut microbiota

IntroductionThiamine (vitamin B1) in the gut is crucial for maintaining intestinal homeostasis and host health. Our previous study identified significantly lower levels of fecal thiamine in individuals with obesity; however, its potential and mechanisms for alleviating obesity induced by a high-fat...

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Bibliographic Details
Main Authors: Yu Xia, Lulu Wang, Yanyan Qiu, Weihong Ge
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Nutrition
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Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2025.1532581/full
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